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Pathways of post thaw apoptosis

Published on: Wednesday 10, February 2010

Stroh, C., et al., The role of caspases in cryoinjury: caspase inhibition strongly improves the recovery of cryopreserved hematopoietic and other cells. Faseb J, 2002, ,16(12): p. 1651-3.

 

The article describes activation of caspase 3 during freezing and the influence of caspase inhibition on post thaw recovery.  Why we like it: The article demonstrates the pathways activated when cells undergo post thaw apoptosis.  The work is rigorous and interesting.